evidence House of Commons'

committee, 1871, 568-570;

prescribed, 406; tolerated re-
sistance, 407.
Russian Emperor Alexander cau-
tioned by Jenner against
Walker, 329; an unprofitable
interview, 362.

Sacco, Dr., Milan, uses horsegrease,
264, 267, 336, 512, and sup-
plies De Carro of Vienna, 265,
405; his cowpox transmitted
through De Carro to India,
385; exploits as vaccinator,
403-404, 406.

Salvani, vaccine missionary, 401.
Salivation, 519.

Sanitation, new faith, 448, 474, 477.
Sancho, William, 258.
Sangrado, 571.

Scarlet fever inoculated, 359; in
Newcastle, 428, 430; increased
and intensified since vaccina-
tion, 448; in England and
Wales, 1838-40, 505, 506.
Scheuchzer, Dr., variolation, 1721-
28, 32.

Schleisner, Dr., Icelandic smallpox,

420-421.
Schultz, Dr., 62.
Sclater-Booth, G., 576.
Scotland, smallpox and variolation

in 18th century, 50; smallpox
an infantile disorder, 51;
smallpox among vaccinated,
1818-19, 366; statistics of
smallpox, 1859 to 1872, 534;
Compulsory Act, 1863, 563.
Scott, Dr. Helenus, 385, 388, 392.
Scott, Dr. John, 591.
Scott, Sir Walter, 371.

Scrofula excited by variolation,

166, and vaccination, 515.
Scurvy, prevalence in 18th century,
87; influence on smallpox,
521.

Seaford, Sussex, 83.
Seaton, Dr. E. C., Handbook of

Vaccination, smallpox cowpox,
75; mendacious letter, 485-
497; ruling spirit of Epidemi-
ological Society, 486; intrigues
for place and power, 495;

ruthless, untruthful, mercen-
ary, 578.
Sebright, Sir John, 247. [401.
Seville, fatalities from vaccination,
Sewell, Mr., attempts to produce

cowpox from horsegrease, 335.
Sewell's Point, Boston, 58.
Shaftesbury, Lord, neglected vacci-

nation, 481; improved houses
might exterminate smallpox,
482.
Sherborne, Lord, 183, 184, 185.
Shrapnell, Mr., 171, 269.

Sievier, statue of Jenner, 363.
Siljeström, P. A., smallpox in
Sweden, 417-419.

Simmons, Mr., Manchester, experi
ments with horsegrease, 133,

155.
Simon, John, recitation of Jennerian
legend, 103; Jenner's master-
piece, 124, 142, 155, 156, 158,
333; Papers on History and
Practice of Vaccination, 510-
519; terrible tales, 511; Lon.
don smallpox, 511-512; cowpox
derived from smallpox and
infallible prophylaxy thereof,
512-513, 525; misstatement of
Jenner's prescription, 513,525;
all vaccination assumed effec-
tive, 514; drawbacks unfairly
stated, 515; scrofula, 515;
admitted dangers, 515; quali-
ties of virus unknown, 516;
syphilis, 516; difficulties of
vaccination, 516; sickly chil-
dren, 517; selection of virus,
517; an ideal rarely realised,
518; questions addressed to
500 medical men, 518; answers
predetermined, 519; value and
characteristics, 524-525; evi-
dence House of Commons'
committee, 1871, 557; un-
scrupulous character, 558;
ruthless, untruthful, mercen-
ary, 578.
Simonds, Professor J. B., cowpox
a questionable disease, 272.

Simpson, James, 189.

Sims, Dr., 187, 226, 331.

Skey, Dr., 189.

Sloane, Sir Hans, 15, 23; Newgate
experiment, 17; cautious
counsels, 17.
Smallpox an infantile disease in
Scotland, 51, 242, 445; epi-
demic, 1818-19, 367; in China,
394; in Sweden, 409-410; in
Norwich, 436; in Glasgow,
440; disease of young and
poor, 26, 437, 440, 445, 470.

An alternative of other dis-
eases, in Sweden, 415-417; in
Newcastle, 428; in Glasgow,
439-444; the fact enforced by
Dr. Farr, 447-451; by John
Gibbs, 504-506; by Professor
F. W. Newman, 546; by Dr.
Bakewell, 560; by Malthus,
570; the disease to be studied
with its congeners, 511; epi-
demic of 1871, 570-571.

In London, 1701-1722, 24-25;
18th century, 77-87; 1791 to
1820, 346; development of
fabulous salvation, 466-468;
decline prior to vaccination,
86, 211, 466-467.

In England and Wales, con-
jectural mortality, 25, 194,
208-209, 345; case according
to John Gibbs, 505, 507;
fabulous salvation, 526-528.

In Boston, 3-6, 371-373;
Chester, 69; China, 394 ;
Edinburgh,49-51, 366; Geneva,
61-62; Glasgow, 439-445; New-
castle, 424-430; New England,
1787, 84, 374; Norwich, 432-
438; Sweden, 408-419.

Declining prior to introduc-
tion of vaccination in London,
86, 222-225, 466-467, 487; over
Europe, 368, 431, 446, 468,
476, 514; in Vienna, 369;
Sweden, 410, 414-416; Italy,
404; Denmark, 419; Glasgow,
446; Dr. Farr's evidence, 86,
211, 466-467.

Exaggerated horrors, 76,

430, 570; Massey's evidence,
23; Wagstaffe's, 24; Monro's,
50; Haygarth's, 69; Birch's,
85; multitudes never had
smallpox, 65; unknown for
years in some parts of England,
83; rarity in Norwich, 433;
disease ever had some limit,
210, 431; wild assertions of
House of Commons' committee,
212; terrible tale of Mexico,
511.

Rate of mortality prior to
vaccination in Boston, 3, 372;
Christ's Hospital, 23, 524;
London, 24-25, 26, 31, 79-80,
373; Halifax, Rochdale, Leeds,
30; Edinburgh, 50; London
Smallpox Hospital, 66; New-
castle, 427; Glasgow, 440;
according to Dr. Buchan, 66,
and Edinburgh Review, 66.

Increased by variolation,
69, 72, 236, 246, 390, 426, 431,
462-464.

Intensified by maltreatment,
84, 427, 437, 521; by food,
87, 316, 521.

Sporadic character, 209, 522,
568.

Origin in horse according to
Jenner, 97, 359, 513.
Smallpox cowpox introduced, 75;
connection with cowpox denied
273; cows contract smallpox
from milkers, 378-379; Ceely
and Badcock, 75, 272, 472,
514, 528; unqualified con-
fidence of Simon, 512-513, and
Robert Lowe, 528.

Smith, Dr. Southwood, absolute
faith in sanitation, 478, 556.
Smith, William, cowpox after cow-
pox, 106.

Smith, William, exaltation of
Jenner, 247.

Spain, escaped variolation, 62;
vaccination introduced, 400-
401.

Spencer, Earl, 397.
Spencer, Herbert, increased vacci-
nation and smallpox, 541.

Squirrel, Dr., opponent of vacci
nation, 290, 301, 361.

Stanhope, Earl, 73.

Staunton, Sir George, 394.
Steigertahl, Dr., 17.

Stephens, Joanna, remedies for
stone, 37.
Stepney, 26, 27.

Stevens, Dr., never saw injury
from vaccination, 566.
Stiles, Henry, smallpox after cow-
pox, 130.
Stockholm, 417-418.

Strickland, Sir George, opposes
compulsion, 483, 485.
St. Andrews, Jenner's purchase of
degree, 97; Ring's sneer at
same, 329, 330.
St. Christophers, 38.
St. Pancras guardians, 587.
Stuart, Lady Louisa, fiction as to
introduction of variolation, 13.
Sunderland, Earl of, son variolated
and killed, 34.

Suttons, eminent variolators, 45,
179, 188; method of practice,
46.
Sweden, variolation introduced,
62, but little practised, 408;
Jenner's pride in, 345, 392;
sorely afflicted with smallpox,
408; influence of famine, 409;
children chief sufferers, 409;
disease aggravated by bad
treatment, 410; steadily de-
clining when vaccination was
introduced, 410-411; vaccina-
tion made obligatory, 1816,
411; means of livelihood for
clergy, 411; asserted exter-
mination of smallpox, 413-414;
Siljeström's evidence, 417-419.
Swarmery, 291.

Swift's city shower, 82.
Swinepox, 98, 99, 262, 401.
Sydenham, 448, 521.
Syphilis, invaccination foreseen by
Massey, 27, and Cobbett, 309;
declared impossible, 68, by
Simon, 516, by H. A. Bruce,
530, and by Sir Dominic Cor-
rigan, 561; Ricord's warning,

Tea introduced, 89; denounced by
Cobbett, 316.

Tebb, William, 580, 587, 596.
Temple, Sir Richard, smallpox and
vaccination in India, 391.
Terry, Dr., 15.
Thiele, Dr., 1836, produces small-
pox cowpox, 512.
Thomson, Dr., Boston, 5.
Thomson, Dr. John,

smallpox
epidemic in Scotland, 1818-19,
366; depressing experience
with vaccination, 366-368;
receives equine virus from
Jenner, 368; absence of epi-
demic smallpox when vaccina-
tion was introduced, 369.
Thornton, Dr., 190.
Thorpe, Rev. R. A., 448.
Thurlow, William, 590.
Timoni, Emanuel, 1, 2, 7, 10.
Tortworth, eight paupers cow-
poxed, 107.

Travers, Benjamin, 217, 218, 219.
Trinidad, vaccination in, 559.
Tronchin, Dr., variolator, 60.

Trotter, Dr., smallpox in navy,
397; medal for Jenner, 398.
Turgot, 59.

Turkey, variolation, 1, 9, 11;
malignity of smallpox, 12.
Turner, Mr., experiments with
horsegrease, 335.

Turton, Sir Thomas, 250-251, 252.

Underwood, Dr., 383.

United States, vaccination intro-
duced, 370-382.
Urquhart, William, 34.

Vaccination, origin of term, 229;
vaccinium and vacciolation,
220, 222, 229.

Precipitate approval of Lon-
don physicians, 70, 173; Dr.
Pearson's work, 151, 170;
acceptance by King and Court,
171; the heir of variolation,
174, 191, 249, 370, 395; received
with acclamation, 274, 405;
offered gratis, 236, 326-327;
means by which promoted,
275; character of furore, 278,
299, 305; public goaded to
belief, 286; fury of controversy,
290, 305; swarmery, 291;
favoured by decline and ab-
sence of smallpox, 222-225,
369, 476, 487, 514, 562.

Tables of comparison and
advantage, 214, 377.

Disrepute in and around
London (1805) 281, 293; abate-
ment of faith under failure
(1808) 308-309, 317, 453;
(1822-23) 364-365, 426; (1825
and 1838) 520; Sir Henry
Holland's testimony (1839)
490; faith never so low as
prior to enforcement of prac-
tice, 477-479; revival of delu-
sion, 309, 426, 474-475.

Reduction of claim to making
smallpox milder, 238, 288, 313,
321, 338, 566; security exactly
equal to variolation, 339, 355.

Opinion that prophylaxy
wore out, Goldson, 284;

Brown, 288; contested in Edin-
burgh Review, 302; by Thom-
son, 368; asserted by Lord
Ellenborough, 353; denied by
Jenner, 354; condemned by
National Vaccine Establish-
ment (1851), 473.

Failure from reports of
National Vaccine Establish-
ment, 464-466.

Easy art practiced by ladies
and gentlemen, 276, 280, 305,
314, 489; Walker's opinion,
324; practice in Sweden, 411-
413; becomes difficult, 343;
Simon's ideal conditions of
safety and success, 516-518.

In Spanish America, 401-
403; Austria, 404, 506; Ba-
varia, 596; Ceylon, 392-393;
China, 393-395; Denmark, 419;
Dublin, 242-243; Edinburgh,
241-242; Finland, 419; France,
169, 398; Glasgow, 441-446;
Iceland, 420; India, 383-393;
Ireland, 561; North Italy, 403-
404; Newcastle, 426; Norwich,
432-434; Russia, 406; Scotland,
151, 534, 563; Spain, 400;
United Kingdom (1853), 481-
483; United States, 370-382;
Vienna, 404.

Adopted and enforced by
State in England: Cobbett on
projected compulsion (1803),
305-307, (1808), 310-311; estab-
lished and endowed (1808),
250-258; paid for out of poor
rate (1840), 470; enforced
vaccination
(1853), 480-485

office projected, 493-494, 496,
501, with compulsory revac-
cination (1855), 496; compul
sion intensified (1861), 526;
repeated penalties enacted
(1867), 538, 540-541, 550; re-
ported against by House of
Commons' committee (1871),
571; House of Commons con-
curs, 572; rejection by House
of Lords and submission of
Commons, 572-573; erratic and

arbitrary administration of the
law, 575-576; Evesham letter
(1876), 576; subsequent at-
tempts to modify law, 577.

Law detested by the poor,
479; why abhorred, 501; cruel
and despicable persecution,
590-592; hated in Lancashire,
591.

Vaccination as a trade, 470,
479, 480, 485, 488-489, 493,
496, 518, 519, 533, 536, 537,
580; public practice worth
£100,000 a year, 583.
Vaccination Inquirer, 580.
Vaccination Tracts, 581.
Vaccine girdle round the world, 401.
Vaccine Pock Institution founded,

1799, 159, 251; Jesty's visit,
205; reward offered for small-
pox after cowpox, 258; con-
sequently shut up, 259.
Vaccine roses, 332.
Vaccine Scourge, 325.
Vaccinoff, a Moscow foundling, 406.
Vantandillo, Sophia, prosecution,
462.

Variolation practised in Tur-

key, 1, 9, 11; introduced to
Boston, 2-7; to England, 12-
14; experiment in Newgate,
15-17; on charity children, 17;
children of Prince of Wales,
18; Maitland's operations, 19-
20, easy acceptance of practice,
22, 28; opposition of Masseys,
23-28, 31-34; Dr. Nettleton's
practice, 30; Jurin's precau-
tions, 30-31; Dr. Scheuch-
zer's tabulation of cases, 32;
Dr. Wagstaffe's observations,
33; disasters, 34; the position
(1728), 35-36.

Revival of practice under
Dr. Mead (1748), 36-37, 39-
40; in Smallpox Hospital, Cold
Bath Fields, 40; sermon of
Bishop Maddox, 40; theo-
logical opposition, 42; approval
of London College of Physi-
cians (1754), 43; etiquette of
practice, 44; Mrs. Chapman's

procedure, 44; Jenner's ac-
count of preparatory regimen,
45; Suttons' methods, 45-47 ;
Dr. Dimsdale's, 47-49; Society
for General Inoculation (1775),
49; extent of variolation, 52;
Dr. Buchan's evidence, 53-55;
practice in New England, 56-
59; France, 59-61; Geneva,
61-62; Empress Catharine, 62-
65; fatalities, 66-69; cleared
the way for vaccination, 70;
Dr. Lettsom on dangers, 71;
Wilberforce urgent for sup
pression, 71; denounced by
Dr. Mathews, 71; by Sturges
Bourne, 72, 246: by Jenner,
72; by Lord Henry Petty,
246; Lord Boringdon's bill,
73; successful prosecution for
exposure (1815), 73, 462; Dr.
Epps (1831), 74; prohibited
by Act of Parliament (1840),
74, 470, 464; Dr. Gregory's
regret, 74; revived by Ceely
and Badcock (1839-40), 75-76.

Practised in China, 16, 394,
India, 392, Italy, 62, Persia,
394, Scots Highlands, 29,
Wales, 29.

Introduced to Barbados, 38;
Boston, 2, 7, 11, 57-59, 371-
374, 377; Florence, 62; France,
59; Geneva, 61; Germany, 62;
Holland, 62; Ireland, 474;
Newbury, 44; New England,
56; Newcastle, 445; Norwich,
435, 437; Paris, 60; Phila-
delphia, 38; Rome, 62; Rus-
sia, 62-65; St. Christophers,
38; Scotland, 50; Spain, 62;
Sweden, 62, 408.

Practised from arm to arm,
63, 120, 193; Jenner asserts
its happy effects, 123; un-
certainty of operation, 105,
108, 166, 212; cannot affect
smallpox, Hamernik, 522;
effects governed by mode and
conditions, 150.

A pest and a terror, 71, 72,
213; an excitant of scrofula,