CHRONIC CATARRHAL DISEASES. Chronic catarrh never fails to indicate general constitutional debility. Local treatment is always desirable, but for permanent results efforts must be directed toward promoting general functional activity throughout the body, and a general increase of systemic vitality. The notable capacity of Gray's Glycerine Tonic Comp. in this direction readily accounts for the gratifying results that can be accomplished through its use in the treatment of all chronic catarrhal affections, but especially those of the gastro-intestinal canal and respiratory tract. The particularly gratifying features in the results accomplished by Gray's Glycerine Tonic Comp. are their substantial and permanent character. This is naturally to be expected, since they are brought about through restoring the physiologic balance of the whole organism.

THE PNEUMONIA CONVALESCENT. While the course and progress of acute lobar pneumonia is short, sharp and decisive, the impression made upon the general vitality is often profound, and apparently out of proportion to the duration of the disease. Even the robust, sthenic patient is likely to emerge from the defervescent period with an embarrassed heart and general prostration. In such cases the convalescent should be closely watched and the heart and general vitality should be strengthened and supported, and this is especially true as applied to the patient who was more or less devitalized before the invasion of the disease. For the purpose indicated. strychnia is a veritable prop upon which the embarrassed heart and circulation can lean for strength and support. As a general revitalizing agent is also needed at this time. it is an excellent plan to order Pepto-Mangan (Gude).

to which should be added the appropriate dose of strychnia, according to age, condition and indications. As a general tonic and bracer to the circulation, nervous system and the organism generally, this combination cannot be surpassed.

STUBBORN CASES OF RHEUMATISM.

"Many stubborn cases of rheumatism respond rapidly to the influence of Tongaline. This product, representing the highest degree of pharmaceutical skill, contains the salicylates in an unusually potent form, because they are not obtained by synthesis, but from the natural oil. In addition to their potency as anti-rheumatics, they possess the advantage of not deranging the stomach."

Physicians who appreciate honest pharmacy. will find in Tongaline a product worthy of their highest commendation and confidence.

PROPHYLAXIS AGAINST "COLDS."

In the case of a great many persons who each winter suffer severely from "colds" even involving the smaller bronchi, one of the most successful means of guarding against such infections is the systematic use of Cord. Ext. Ol. Morrhuae Comp. (Hagee) during the winter sea

son.

By means of this cod liver oil product, which is exceptionally palatable, the tissues, particularly the tissues of the respiratory tract, are increased in resisting power against microbic invasion, in which phenomenon, of course, is to be sought the explanation of the power of Cord. Ext. Ol. Morrhuae Comp. (Hagee) to reduce the likelihood of "colds."

GLYCO-THYMOLINE IN TYPHOID FEVER.

To keep the alimentary tract as free as possible from fermentable matter, to inhibit as far as possible the activity of the putrefactive bacteria which normally inhabit the intestinal canal, and to eliminate the toxin produced by the Bacillus Typhosus as rapidly as possible are desirable results to accomplish in treating typhoid cases.

The power of Glyco-Thymoline to produce these results is amply proven by the clinical reports from eminent physicians in all parts of the country.

The distressing condition of fissured tongue and "cracked" lips is immediately relieved and the

sordes of teeth and mouth quickly removed by the use of Glyco-Thymoline.

XXX

PAIN: ITS RELIEF.

If ever direct methods are needed it is in the relief of pain. And the application of a direct method in pain embraces, of course, the administration of a reliable and effective anodyneand such an agent should be free, to the greatest extent, from evil effects

A product that answers these requirements of an anodyne is Papine (Battle). Its effect is prompt and positive, and it possesses a minimum of bad effects. For these reasons Papine is entitled to first rank among pain-relieving agents.

OF DISTINCTIVE VALUE.

Pluto Water possesses, in addition to the properties of plain water, a mildly tonic effect upon the mucous membranes of the stomach, due to both its gases and its salts, and, owing to its water and its salts, it is also diuretic. It is exceedingly useful, when taken half an hour before meals, to cleanse the gastric membranes and to prepare it for the reception of food. It also serves to dilute and wash out waste material from the system through the kidneys. Patients will usually drink Pluto Water who will not, or cannot, drink sufficient ordinary water. A glass taken an hour or two after a meal promotes digestion, and helps remove the effete products from the blood. In fevers it is always useful and should be given freely; and it often allays nausea and vomiting. In short, Pluto water has a distinctive place and value in metabolic therapya fact which is widely recognized and testified by the way in which it is used and prescribed by physicians everywhere.

A SEDATIVE IN SEXUAL IRRITATION.

It is in irritation of the sexual centres, manifested by exaggerated desire, premature ejaculation with lack of relief following, sleeplessness and a general instability of the nervous system, that Pasadyne (Daniel) will exert a marked influence of a beneficial character.

A quality that gives an added value to Pasadyne is its freedom from untoward effects. It is well known that this product is a preparation of passiflora incarnata, the name Pasadyne distinguishing it from inferior products and preventing substitution.

A sample bottle may be had by addressing the laboratory of John B. Daniel, Atlanta, Georgia.

SPECIFY THE BRAND!

Every now and then one is forcibly reminded of the fact that the pharmaceutical market of today contains many so-called therapeutic agents of doubtful medicinal value-agents of indefirite and varying potency. The point was well brought out, not so very long ago, by a certain chemist who purchased in the open market ten samples of tincture of opium in which the content of morphine varied from 2.7 to 22.8 per cent. Of three tinctures of aconite which he

The Meaning of Substitution to the Physician.

The substitutor prescribes for your patient without regard to your reputation or the welfare of your patient, assuming that you do not know your business Why does he do it? For illegitimate profit. What are you going to do about it?

examined, one was found to contain 9 per cent more of aconitine than the standard required, and another 20 per cent less. Two specimens of fluid extract of the same drug contained 18.5 per cent and 25.5 per cent more, respectively, of the alkaloid than is officially required. Samples of belladonna showed 11.5 per cent less of mydriatic alkaloids in the fluid extract of the root, and 17 per cent more in the tincture of the leaves. Some tinctures and fluid extracts of nux vomica revealed an excess of strychnine-in one case of 19 per cent.

The foregoing facts are called to mind by an announcement which is appearing in medical journals over the signature of Parke, Davis & Co., bearing the title, "Fluid Extracts and Tinctures of Definite Potency," and opening with this significant question: "When writing a prescription for a fluid extract or tincture, what assurance have you that the product dispensed will be medicinally efficient?-that it will be active, yet not too active?-that it will produce the therapeutic result that you hope for and expect?"

It is well known that Parke, Davis & Co. are authorities upon the subject of standardization, chemical and physiological, and it may be confidently asserted that the practitioner of medicine who reads and ponders what is said in the announcement referred to will find that his time has been well expended. The physician's obligation to his patient, it should be remembered, does not cease with the writing of a prescription. There remains the further duty to assure himself that trustworthy products are used in compounding that prescription. When he prescribes a fluid extract or tincture the physician owes it to his patient to specify the brand-the brand of a reliable manufacturer.

The other day, a visiting physician told us of an experience which he had in a large western city. He wanted to try emetine hydrochloride in the treatment of a case of pulmonary hemorrhage in the hospital with which he is connected. He telephoned to a number of drug stores to find Abbott ampules of this alkaloid. He could not find any. Therefore, the patient went without the treatment—and kept on bleeding.

This doctor was astounded to learn that The Abbott Alkaloidal Company has a branch in that very city; also that the drug wholesalers in that town carry stocks of our preparations.

Moral: Don't be too sure that you can't get Abbott's alkaloids and specialties in your own city. Tell your druggist to call up his jobber over the 'phone and ask for the things he wants. The chances are he can secure them without trouble.

But here is another moral. If you like Abbott goods (as I am sure you do), and if you prescribe (as very likely you do), your druggist should carry in stock all those preparations of ours which you use constantly. Why not urge him to do so. If you don't want to "bother" to do this, tell us your druggist's name and we will get in touch with him.

There are splendid opportunities for thousands

of druggists in every part of our country to carry complete lines of our goods. In every city of considerable size there should be at least one druggist who can make himself Abbott "headquarters" for that city and the surrounding country.

If you know of any druggist who wants a chance like this-it is a good one, I assure you— won't you help us "get together"?

炭

PLACING THE BLAME.

At the present day much discussion is being heard on every side concerning the role of the intestinal canal in the causation and development of innumerable diseases. Once the liver was the chief malefactor, and a disordered liver, if not blamed as the chief cause of pretty nearly every disease that "human flesh is heir to,' was sure to be considered particeps criminis. As the indictment of the liver has been narrowed and its culpability brought within more specific limits, some other culprit has become necessary. How natural to turn to the liver's closest associate and known accomplice, the intestinal tract. Thus it is that the "human cesspool," as Sir Wm. Arbuthnot Lane has styled the intestinal canal, has had to stand accused of the etiologic crimes that the liver is no longer held accountable for.

But, as always happens, interest in the depravity of the new culprit has made the actual misdeeds of the old lose much of their importance. And so, gradually but none the less surely we have grown to ignore the crimes of the liver, until at last in our indignation at and fear of the intestines, we are almost ready to look upon the liver as more sinned against than sinning," a victim of hasty and unwarranted accusation.

66

With this state of affairs, it is not surprising that the liver, wily and dangerous old offender that it is, has been allowed to perpetrate many outrages without being called to account. It is high time that medical men awoke to the fact that the liver is the same old trouble-maker it has always been, and needs watching as closely

as ever.

Indeed, recent study of intestinal stasis and associated conditions has shown that the liver is often the main culprit even in this affection. The action of the bile in controlling intestinal putrefaction, arresting bacterial activity, promoting peristalsis, and assisting digestion makes it highly necessary that this important secretion be frequently interrogated as to its quantity, and any decrease in the bile output given instant and vigorous attention.

This naturally raises the question, what is the best and most effective cholagogue? Many and various hepatic stimulants have been brought forward, but experience has shown that for promoting the functional activity of the liver nothing is superior to Chionia. This is an exceedingly effective preparation of Chionanthus Virginica. Administered in proper dosage it is a powerful hepatic stimulant, increasing the flow of bile, without, however, producing the marked and extreme catharsis that makes so many other hepatic remedies highly objectionable.