that the dengue of 1828 gave a certain degree of immunity from the epidemic of 1850. On looking over my notes, I find among the names of those I then attended, several of the exempts of this year." I am disposed to attribute this exemption rather to the age of the individuals, as it will presently be seen that old persons were especially favored by the break-bone fever. Those still in the prime of life, who had dengue in 1828, had no exemption, so far as my observation went, from break-bone.

'In break-bone fever, hemorrhages were frequent. I find no mention of this symptom either in the East or West-India dengue, or of that of 1828, in Charleston.

'A remarkakle difference, and perhaps one of the most important, was the excessive debility in the break-bone fever, which had no resemblance to anything that we know of the dengue. In the latter disease, the convalescence, except the affections of the joints, was tolerably prompt; in the former, we have seen how different the case was, both in the epidemic I am describing, and that related by Rush.

The sore mouth, so generally observed in dengue, was not one of the symptoms of break-bone fever.

The frequent and sudden shifting of the pain from spot to spot, or from joint to joint, was not seen here.

'In dengue, the disease went hardest with the old; in break-bone fever, it was mild, and, indeed, most of the exemptions I saw were with elderly persons.'

Notwithstanding these differences, Dr.Wragg is willing to admit that the diseases strongly resemble each other in many points. In regard to contagion, Dr. Wragg says 'I do not think it contagious because its invasion was so sudden and general, all over the city, that any attempt to trace it from patient to patient, from house to house, or from quarter to quarter, would utterly fail.' He cites numerous instances of persons going from Charleston to other places, where they were attacked by the disease without communicating it to their attendants.

In respect to treatment, Dr. Wragg says there was but little variation among the physicians of Charleston. Their chief reliance was upon gentle cathartics, stimulants and opiates. He is opposed to the view that 'the disease is essentially self-limiting in its nature,' and believes that it was eminently under the control of medicine.' He says, 'there was a proneness to relapse which almost took the form of periodicity.' For this he gave quinine, but it sometimes proved insufficient, and he then advised a change of air.

Such are the views of Dr. Wragg on this interesting epidemic. The reader may compare them with those of Professor Dickson and surgeon Porter, of the same place and vicinity.

ARTICLE IV.

ON THE MORTALITY OF CHARLESTON.

BY JOHN L. DAWSON, M.D.

A CLASSIFIED TABLE OF THE DEATHS in the City of CHARLESTON, South Carolina, for the Year 1850:

Re-arranged from the Annual Report of John L. Dawson, M.D., the City Registrar,

* As Dr. SIMONDS' classification of diseases has been mostly adopted in the vital statistics of this volume, at our request he has re-arranged the beautiful table of Dr. Dawson, so as to correspond. Dr. Dawson had adopted the classifi cation of the American Medical Association, and we should not have made the change but for the convenience of comparison. -- Ev.

A CLASSIFIED TABLE OF DEATHS, ETC.-continued.

DEATHS IN CHARLESTON, for cach Month and Season of the Year 1850.

REPORTS FROM NORTH CAROLINA.

ARTICLE I.

ON THE TOPOGRAPHY, PREVAILING DISEASES, EPIDEMICS AND PUPLIC INSTITUTIONS IN THE CITY OF RALIEGH, N. C., AND THE SURROUNDING COUNTRY.

[Having received but two reports from this State, both of them from the hands of our esteemed friend Dr. McKEE, of Raleigh, we shall insert them, and doubt not they will repay perusal - especially the one on Vital Statistics. We had hoped to get something from the State Medical Society, but have been disappointed. — ED.]

THE city of Raleigh is located in the county of Wake, near the centre of the State, and is two hundred and eighty-six miles south of Washington City, and one hundred and thirty-seven miles west of the ocean. The population of the city and environs is about four thousand five hundred; and that of the county, including the town, twenty-four thousand four hundred, with twenty-five practising physicians. Raleigh is situated on a granite ridge, which runs from north to south-west, embracing the counties of Franklin, Warren and part of Granville, on the north, and parts of Cumberland, Chatham and Moore, on the south-west. This ridge separates the cretacious from the argillaceous lands, leaving the paludal districts to the east. The soil here is a mixture of clay and sand, and is what is termed the grey lands. West, the country becomes very hilly, and the natural soil is an argillaceous loam, with a clay foundation. As to the forest growth, it is a mixture of red and white oak, blackjack, pine, dogwood, chinquepin, poplar, ash, hickory, gum and elm. In approaching Raleigh, it presents the appearance of a forest, dotted with numerous houses, and quite a picturesque view, as the large dome of the capitol, spires of the churches, and the lofty tops to some of the other buildings, are seen rising above the height of the numerous trees (from which it takes the name of the City of the Oaks'). The city is laid off in squares, and